Abstract Search

ea0063gp159 | Cushing's | ECE2019

Skeletal muscle fatty infiltration in the thigh, as assessed by MRI T2-weighted and 3-point Dixon sequences, is associated with poor performance on muscle function testing in patients with Cushing’s syndrome in remission

Martel Luciana , Alonso Alicia , Bascunana Helena , Manera Jordi Diaz , Llauger Jaume , Nunez-Peralta Claudia , Biagetti Betina , Montesinos Paula , Webb Susan , Valassi Elena

Background: Muscle weakness may persist in patients with Cushings syndrome (CS) long-term after resolution of hypercortisolism, but mechanisms determining this sustained impairment are not known. We hypothesized that alteration of muscle structure, due to fatty infiltration, is associated with muscle dysfunctions in these patients.Patients & methods: Twenty-six CS women [mean(±S.D.) age 49±12 years; mean(±S....

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ea0070aep675 | Pituitary and Neuroendocrinology | ECE2020

Gender dimorphism of intramuscular fatty infiltration and related muscle dysfunction in patients with long-term control of acromegaly

Martel-Duguech Luciana , Alonso-Pérez Jorge , Bascuñana Helena , Diaz-Manera Jordi , Alonso-Jimenez Alicia , Llauger Jaume , Nuñez-Peralta Claudia , Montesinos Paula , Webb Susan M. , Valassi Elena

Background: Muscle weakness persists in patients with acromegaly (ACRO) even long-term after disease control. Mechanisms determining this sustained impairment are not known. We hypothesized that alteration of muscle architecture, due to intramuscular fatty infiltration, is associated with muscle dysfunction in these patients.Patients and Methods: Thirty-seven acromegalic patients [21 females and 16 males, mean (± s.d.)age, 53 ± 9 years...

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Endocrine Abstracts

Skeletal muscle fatty infiltration in the thigh, as assessed by MRI T2-weighted and 3-point Dixon sequences, is associated with poor performance on muscle function testing in patients with Cushing’s syndrome in remission

Gender dimorphism of intramuscular fatty infiltration and related muscle dysfunction in patients with long-term control of acromegaly

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